The World Health Organization’s (WHO) declaration of Mpox as a “public health emergency of international concern” highlights the ongoing risk posed by infectious microbial pathogens. The Mpox virus primarily spreads through close contact with an infected person, contaminated materials, or through contact or consumption of infected animals. Transmission modes vary between different clades of the virus. For example, Clade Ia is typically spread through bushmeat consumption, while Clade Ib and Clade II spread person-to-person. Although the natural reservoir of the Mpox virus remains unknown, small mammals and rodents in West and Central Africa are thought to be potential carriers.